How Toxins Affect Fertility: Dr. Paul Magarelli on Endocrine Disruptors, Sperm Health & IVF (Part 2)

Endocrine-disrupting chemicals (EDCs) are everywhere—in the plastics we touch, the personal care products we use, the pesticides sprayed on our food, and even the air we breathe. But few people realize the powerful and far-reaching impact these chemicals have on fertility, fecundity, and reproductive health.

In this episode of the Practical Nontoxic Living podcast, Sophia Ruan Gushée shares an excerpt from Ruan Living's 40-Day Home Detox masterclass with Dr. Paul Magarelli, a highly respected reproductive endocrinologist. Drawing from decades of clinical experience, Dr. Magarelli breaks down how EDCs may be silently undermining fertility outcomes—including sperm count, egg quality, IVF success rates, and miscarriage risk.

What You'll Learn in This Episode

• The 4 key factors of fertility: sperm, eggs, uterus, and fallopian tubes—and how toxic exposures affect each

• The alarming decline in sperm quality and count, projected to reach near-zero levels by the 2045

• How endocrine disruptors damage DNA integrity in sperm and embryos, affecting implantation and pregnancy success

• How EDCs may contribute to miscarriage 

• The transgenerational impact of chemical exposure on future children’s health and IQ

• Why detoxing your home and habits is an urgent but hopeful step toward protecting reproductive health

Why This Conversation Matters

With over 1,000 known endocrine-disrupting chemicals infiltrating our daily routines, understanding their role in hormone disruption is vital—especially for those planning to conceive or undergoing assisted reproductive technologies (ART) like IVF.

Dr. Magarelli offers evidence-based advice and encouragement on what you can control: reducing your toxic exposures and supporting a healthy, fertile body through conscious lifestyle changes.

From the 40-Day Home Detox

This episode is part of a larger conversation inside Ruan Living’s 40-Day Home Detox—a transformative program designed to help you identify and reduce toxic exposures in your home. Each day offers a new opportunity to detox your environment, improve your well-being, and reclaim your fertility potential. Explore: 40-Day Home Detox.

Final Thoughts

Your fertility doesn’t exist in isolation. It’s influenced by everything you breathe, touch, and absorb. This powerful episode with Dr. Magarelli shines a light on the invisible environmental stressors we can no longer afford to ignore—and offers a hopeful roadmap for taking back control.

👉 Listen now:
How Endocrine Disruptors Harm Fertility & Fecundity | Dr. Paul Magarelli

Other Resources Mentioned In This Episode

• Optimize Your Fertility, Assisted Reproductive Efforts, and Pregnancy Outcomes with Dr. Shanna Swan
• How Toxic Exposures Threaten Women's Fertility and Reproductive Health: Expert Hugh Taylor Explains