Dr. Paul Magarelli explains how endocrine-disrupting chemicals affect fertility and reproductive health

How Toxins Affect Fertility: Dr. Paul Magarelli on Endocrine Disruptors, Sperm Health & IVF (Part 2)

May 29, 2025

Endocrine-disrupting chemicals (EDCs) are everywhere—in the plastics we touch, the personal care products we use, the pesticides sprayed on our food, and even the air we breathe. But few people realize the powerful and far-reaching impact these chemicals have on fertility, fecundity, and reproductive health.

In this episode of the Practical Nontoxic Living podcast, Sophia Ruan Gushée shares an excerpt from Ruan Living's 40-Day Home Detox masterclass with Dr. Paul Magarelli, a highly respected reproductive endocrinologist. Drawing from decades of clinical experience, Dr. Magarelli breaks down how EDCs may be silently undermining fertility outcomes—including sperm count, egg quality, IVF success rates, and miscarriage risk.

What You'll Learn in This Episode

The 4 key factors of fertility: sperm, eggs, uterus, and fallopian tubes—and how toxic exposures affect each
The alarming decline in sperm quality and count, projected to reach near-zero levels by the 2045
How endocrine disruptors damage DNA integrity in sperm and embryos, affecting implantation and pregnancy success
How EDCs may contribute to miscarriage
The transgenerational impact of chemical exposure on future children’s health and IQ
Why detoxing your home and habits is an urgent but hopeful step toward protecting reproductive health

Why This Conversation Matters

With over 1,000 known endocrine-disrupting chemicals infiltrating our daily routines, understanding their role in hormone disruption is vital—especially for those planning to conceive or undergoing assisted reproductive technologies (ART) like IVF.

Dr. Magarelli offers evidence-based advice and encouragement on what you can control: reducing your toxic exposures and supporting a healthy, fertile body through conscious lifestyle changes.

From the 40-Day Home Detox

This episode is part of a larger conversation inside Ruan Living’s 40-Day Home Detox—a transformative program designed to help you identify and reduce toxic exposures in your home. Each day offers a new opportunity to detox your environment, improve your well-being, and reclaim your fertility potential. Explore: 40-Day Home Detox.

Final Thoughts

Your fertility doesn’t exist in isolation. It’s influenced by everything you breathe, touch, and absorb. This powerful episode with Dr. Magarelli shines a light on the invisible environmental stressors we can no longer afford to ignore—and offers a hopeful roadmap for taking back control.

👉 Listen now:
How Endocrine Disruptors Harm Fertility & Fecundity | Dr. Paul Magarelli

Other Resources Mentioned In This Episode

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About Ruan Living

Ruan Living simplifies a nontoxic lifestyle through its Practical Nontoxic Living podcast, free detox workshops, online D-Tox Academy, and transformative 40-Day Home Detox. It aims to help you avoid toxic chemicals, heavy metals, and electromagnetic fields (EMFs) from what you buy, own, and do— without compromising your joy and convenience. Ruan was founded by Sophia Ruan Gushée, author of the bestselling critically acclaimed book A to Z of D-Toxing: The Ultimate Guide to Reducing Your Toxic Exposures and several detox workbooks. A graduate of Brown University and Columbia Business School, Sophia has served on the Brown University School of Public Health Advisory Council and Well+Good Council. A popular nontoxic living speaker, consultant, and teacher, Sophia lives in New York City with her husband and three daughters. Her passion for empowering others to enjoy nontoxic living began with the birth of her first daughter in 2007. Everything she creates is a love letter to her children and for the healthiest, brightest future possible. You can learn more here: Sophia’s Impact.

Disclaimer

This article is for informational purposes only. This information is provided “as is” without warranty.

It is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment and should never be relied upon for specific medical advice. We do not offer medical advice, course of treatment, diagnosis, or any other opinion on your conditions or treatment options. To the extent that this article features the advice of physicians or medical practitioners, the views expressed are the views of the cited expert and do not necessarily represent the views of Ruan Living.

In no event will Sophia Ruan Gushee or Ruan Living be liable for any damages or loss of any kind resulting from the use of this website. Anyone relying upon or making use of the information on this website does so at his or her own risk.

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